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By reducing fat mass and improving adipose tissue signaling, retatrutide may: Lower inflammatory cytokines Improve adipose tissue health Reduce metabolic stress on the liver, pancreas, and cardiovascular system These effects support broader metabolic improvement beyond cosmetic weight loss

These work by reducing inflammation, but they're typically only used when symptoms are very bothersome

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[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Mazurowska L., Mojski M

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